| Product Name | Girdin (phospho Ser1417) Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | APE, GIV, GRDN, HkRP1, KIAA1212 |
| Product description | girdin IS a ubiquitously expressed actin binding protein that plays an important role in the formation of stress fibers and lamellipodia. Subsequent to phosphorylation by Akt, Girdin accumulates at the leading edge of migrating cells and appears to be crucial for the integrity of the actin cytoskeleton and for cell migration.1) Enomoto A., Dev. Cell 9:389-402(2005). |
| Immunogen | Girdin (phospho Ser1417) antibody was raised against a peptide sequence around phosphorylation site of Serine 417 (L-E-M (p)-A-Q) derived from Human Girdin . |
| Modification | p-Ser1417 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHC |
| IHC:1:50~1:200 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | HumanMouse |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | CCDC88A |
|---|---|
| Alternative Names | APE GIV GRDN HkRP1 KIAA1212 |
| Molecular Weight(MW) | 216 kDa |
| Tissue Specificity | The antibody detects endogenous levels of Girdin only when phosphorylated at serine 1417. |
| Entrez Gene | 55704 |
|---|---|
| Protein Accession | NP_060554.3 |
| Application Notes | IHC:1:50~1:200 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store antibody at -20˚C for up to one year. |
| Storage Buffer | Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
