| Product Name | Anti-Phospho-Girdin (Ser1417) antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Synthetic peptide conjugated with KLH |
| Modification | p-Ser1417 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | CCDC88A |
|---|---|
| Gene Synonyms | APE GIV GRDN PEHO HkRP1 PEHOL GIRDIN KIAA1212 |
| Gene Full Name | coiled-coil and HOOK domain protein 88A |
| Gene Summary | This gene encodes a member of the Girdin family of coiled-coil domain containing proteins. The encoded protein is an actin-binding protein that is activated by the serine/threonine kinase Akt and plays a role in cytoskeleton remodeling and cell migration. The encoded protein also enhances Akt signaling by mediating phosphoinositide 3-kinase (PI3K)-dependent activation of Akt by growth factor receptor tyrosine kinases and G protein-coupled receptors. Increased expression of this gene and phosphorylation of the encoded protein may play a role in cancer metastasis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011] |
| Alternative Names | AKT iphosphorylation enhancer Akt phosphorylation enhancer APE Ccdc88a Coiled coil domain containing 88A Coiled coil domain containing protein 88A Coiled-coil domain-containing protein 88A FLJ10392 G alpha interacting vesicle associated protein G alpha-interacting vesicle-associated protein Galpha interacting vesicle associated protein Girders of actin filament Girdin GIV GRDN GRDN_HUMAN HkRP1 Hook related protein 1 Hook-related protein 1 KIAA1212 |
| Molecular Weight(MW) | 216 kDa |
| Cellular Localization | Cell membrane, Cell projection, Cytoplasm, Cytoplasmic vesicle, Cytoskeleton, Membrane. |
| SwissProt ID | Q3V6T2 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% sodium azide,40% Glycerol. |
