Application
Immunohistochemistry staining of GPR44 in thymus tissue using GPR44 Antibody.| Product Name | GPR44 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | PTGDR2, CD294, CRTH2, CD294 antigen, DP2, DL1R, G protein-coupled receptor 44, G-protein coupled receptor 44, HCRTH2, DP2 prostaglandin receptor, GPR44, Prostaglandin D2 receptor 2 |
| Product description | GPR44, also called CRTH2, is a Prostanoid Receptor that binds prostaglandin D2. PGD2 signals through CRTH2 to induce Th2, eosinophil, and basophil chemotaxis in a G-alpha(i) dependent manner. CRTH2 may play a role in mast cell-mediated immune responses such as those involved in allergic reactions. This receptor is upregulated in activated T helper-2 (Th2) cells, peripheral blood basophils, and eosinophils, but not in Th1 lineage cells. It may be a useful marker for Th2 and Tc2 cells. |
| Immunogen | GPR44 antibody was raised against a peptide located in the C-Terminal cytoplasmic domain of GPR44 (Human). |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | ELISAIHC |
| GPR44 antibody can be used in immunohistochemistry starting at 10 μg/mL.: |
|
| Species Reactivity | GorillaHuman |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | PTGDR2 |
|---|---|
| Alternative Names | PTGDR2 CD294 CRTH2 CD294 antigen DP2 DL1R G protein-coupled receptor 44 G-protein coupled receptor 44 HCRTH2 DP2 prostaglandin receptor GPR44 Prostaglandin D2 receptor 2 |
| Tissue Specificity | BLAST analysis of the peptide immunogen showed no homology with other human proteins, except KCNN2 (50%). |
Application
Immunohistochemistry staining of GPR44 in thymus tissue using GPR44 Antibody.| Application Notes | GPR44 antibody can be used in immunohistochemistry starting at 10 μg/mL.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | GPR44 antibody should be stored long term (months) at -80 ˚C and short term (days) at 4 ˚C. As with all antibodies avoid freeze/thaw cycles. |
| Storage Buffer | PBS, 0.1% sodium azide. |
