Application
Western blot analysis of lysate from human brain tissue lysate, using Syncytin(ERVWE1) Antibody at 1:1000 at each lane.| Product Name | HERV Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Many different human endogenous retrovirus (HERV) families are expressed in normal placental tissue at high levels, suggesting that HERVs are functionally important in reproduction. The protein, also known as syncytin, is expressed in the placental syncytiotrophoblast and is involved in fusion of the cytotrophoblast cells to form the syncytial layer of the placenta. This protein has the characteristics of a typical retroviral envelope protein, including a furin cleavage site that separates the surface (SU) and transmembrane (TM) proteins which form a heterodimer.1) Oluwole,S.O., Amyotroph Lateral Scler(2), 67-72 (2007) |
| Immunogen | This HERV (ERVWE1) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 400-429 amino acids from the Central region of human HERV (ERVWE1). |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| For WB starting dilution is: 1:1000 | |
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Unpurified |
| Gene Symbol | ERVW-1 |
|---|---|
| Alternative Names | Syncytin-1 Endogenous retrovirus group W member 1 Env-W Envelope polyprotein gPr73 Enverin HERV-7q Envelope protein HERV-W envelope protein HERV-W_7q212 provirus ancestral Env polyprotein Syncytin Surface protein SU gp50 Transmembrane protein |
| Molecular Weight(MW) | 60 kDa |
Application
Western blot analysis of lysate from human brain tissue lysate, using Syncytin(ERVWE1) Antibody at 1:1000 at each lane.| Application Notes | For WB starting dilution is: 1:1000 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | Supplied in PBS with 0.09% (W/V) sodium azide. |
