Application
Antibody used in WB on Human 721_B cells at 0.2-1 ug/ml.Application
Antibody used in IHC on Human Liver at 5.0 ug/ml.| Product Name | HMGN1 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | HMGN1, FLJ27265, FLJ31471, HMG14, MGC104230, MGC117425 |
| Product description | Chromosomal protein HMG14 (HMGN1) and its close analog HMG17 (MIM 163910) bind to the inner side of the nucleosomal DNA, potentially altering the interaction between the DNA and the histone octamer. The 2 proteins may be involved in the process that maintains transcribable genes in a unique chromatin conformation. Their ubiquitous distribution and relative abundance, as well as the high evolutionary conservation of the DNA-binding domain of the HMG14 family of proteins, suggest that they may be involved in an important cellular function.Chromosomal protein HMG14 and its close analog HMG17 (MIM 163910) bind to the inner side of the nucleosomal DNA, potentially altering the interaction between the DNA and the histone octamer. The 2 proteins may be involved in the process that maintains transcribable genes in a unique chromatin conformation. Their ubiquitous distribution and relative abundance, as well as the high evolutionary conservation of the DNA-binding domain of the HMG14 family of proteins, suggest that they may be involved in an important cellular function.[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.1) Zhu, N. (2007) Mol. Cell. Biol. 27 (24), 8859-8873. |
| Immunogen | Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human HMGN1. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | ELISAWB |
| HMGN1 antibody can be used for detection of HMGN1 by ELISA at 1:312500. HMGN1 antibody can be used for detection of HMGN1 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | HMGN1 |
|---|---|
| Alternative Names | HMGN1 FLJ27265 FLJ31471 HMG14 MGC104230 MGC117425 |
| Molecular Weight(MW) | 11 kDa |
Application
Antibody used in WB on Human 721_B cells at 0.2-1 ug/ml.
Application
Antibody used in IHC on Human Liver at 5.0 ug/ml.| Positive Control | 1) 721_B Cell Lysate |
|---|---|
| Application Notes | HMGN1 antibody can be used for detection of HMGN1 by ELISA at 1:312500. HMGN1 antibody can be used for detection of HMGN1 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.: |
| Form | Liquid |
|---|---|
| Storage Instructions | For short periods of storage (days) store at 4˚C. For longer periods of storage, store HMGN1 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles. |
| Storage Buffer | Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL. |
