Application
Western blot analysis in HL-60 cell line lysates (35ug/lane).| Product Name | HTR1B Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | 5-hydroxytryptamine receptor 1B, 5-HT-1B, 5-HT1B, S12, Serotonin 1D beta receptor, 5-HT-1D-beta, Serotonin receptor 1B, HTR1B, HTR1DB |
| Product description | The neurotransmitter serotonin (5-hydroxytryptamine; 5-HT) exerts a wide variety of physiologic functions through a multiplicity of receptors and may be involved in human neuropsychiatric disorders such as anxiety, depression, or migraine. These receptors consist of several main groups subdivided into several distinct subtypes on the basis of their pharmacologic characteristics, coupling to intracellular second messengers, and distribution within the nervous system (Zifa and Fillion, 1992 [PubMed 1359584]). The serotonergic receptors belong to the multigene family of receptors coupled to guanine nucleotide-binding proteins.1) Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010) Kiezebrink, K., et al. World J. Biol. Psychiatry 11(6):824-833(2010) Mekli, K., et al. Eur Neuropsychopharmacol (2010) In pressPinheiro, A.P., et al. Am. J. Med. Genet.Neuropsychiatr. Genet. 153B (5), 1070-1080 (2010)Cross, D.S., et al. BMC Genet. 11, 51 (2010) : |
| Immunogen | This HTR1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 225-253 amino acids from the Central region of human HTR1B. |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| For WB starting dilution is: 1:1000: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | HTR1B |
|---|---|
| Alternative Names | 5-hydroxytryptamine receptor 1B 5-HT-1B 5-HT1B S12 Serotonin 1D beta receptor 5-HT-1D-beta Serotonin receptor 1B HTR1B HTR1DB |
| Molecular Weight(MW) | 44 kDa |
| Sequence Similarities | Predicted species reactivity based on immunogen sequence: Pig |
Application
Western blot analysis in HL-60 cell line lysates (35ug/lane).| Application Notes | For WB starting dilution is: 1:1000: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | Supplied in PBS with 0.09% (W/V) sodium azide. |
