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IGF2BP2 Antibody

Catalog Number:OM281733
OM281733
Discount Price
OM281733-100ul
1~2 Week
100ul
OM281733-50ul
50ul
OM281733-20ul
20ul
1~2 Week
Product Profile
Product Name IGF2BP2 Antibody
Antibody Type Primary Antibodies
Antigen Alias Insulin-like growth factor 2 mRNA-binding protein 2, IGF2 mRNA-binding protein 2, IMP-2, Hepatocellular carcinoma autoantigen p62, IGF-II mRNA-binding protein 2, VICKZ family member 2, IGF2BP2, IMP2, VICKZ2
Product description This gene encodes a member of the IGF-II mRNA-binding protein (IMP) family. The protein encoded by this gene contains several four KH domains and two RRM domains. It functions by binding to the 5' UTR of the insulin-like growth factor 2 (IGF2) mRNA and regulating IGF2 translation. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.1) Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Immunogen This IGF2BP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 530-556 amino acids from the C-terminal region of human IGF2BP2.
Key Feature
Clonality Polyclonal
Isotype Ig
Host Species Rabbit
Tested Applications FACSIHC-PWB
For WB starting dilution is: 1:1000 For IHC-P starting dilution is: 1:50~100 For FACS starting dilution is: 1:10~50:
Species Reactivity Human
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Symbol IGF2BP2
Alternative Names Insulin-like growth factor 2 mRNA-binding protein 2
IGF2 mRNA-binding protein 2
IMP-2
Hepatocellular carcinoma autoantigen p62
IGF-II mRNA-binding protein 2
VICKZ family member 2
IGF2BP2
IMP2
VICKZ2
Molecular Weight(MW) 66 kDa
Sequence Similarities Predicted species reactivity based on immunogen sequence: Mouse
Database Links
Entrez Gene 10644
Protein Accession Q9Y6M1
Application

Application

Flow cytometric analysis of HepG2 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Application

IGF2BP2 antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human spleen tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.

Application

Western blot analysis in HepG2 cell line lysates (35ug/lane).
Application Notes For WB starting dilution is: 1:1000 For IHC-P starting dilution is: 1:50~100 For FACS starting dilution is: 1:10~50:
Additional Information
Form Liquid
Storage Instructions Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Storage Buffer Supplied in PBS with 0.09% (W/V) sodium azide.
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