Application
Immunohistochemistry staining of IL-1 alpha in spleen tissue using IL-1 alpha monoclonal Antibody.| Product Name | IL-1 alpha Antibody, Monoclonal |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | IL1A, Hematopoietin-1, IL-1 alpha, IL1, IL1-ALPHA, IL1 Alpha, Interleukin-1 alpha, IL-1A, IL1F1, Pro-interleukin-1-alpha, Preinterleukin 1 alpha, Interleukin 1, alpha |
| Product description | Interleukin 1 alpha is synthesized as a 31 kDa promolecule that does not contain a signal sequence. Following proteolytic cleavage, the mature 17 kDa molecule is released as a result of cell injury or apoptosis. IL-1 alpha stimulates bone osteoclast activity, has a role in the modulation of extracellular fluid calcium homeostasis and apoptosis, activates T and B lymphocytes and NK cells, and functions in development. Movement of the IL-1 alpha promolecule to the nucleus in response to endotoxin where it augments transcription of proinflammatory genes has also been documented. |
| Immunogen | IL - 1 alpha monoclonal antibody was raised against Ni-NTA purified recombinant human IL-1alpha expressed in E. Coli strain BL21 (DE3) |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG2a |
| Host Species | Mouse |
| Tested Applications | ELISAIHCWB |
| IL-1 alpha antibody can be used in ELISA, and immunohistochemistry starting at 20 μg/mL.: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | IL1A |
|---|---|
| Alternative Names | IL1A Hematopoietin-1 IL-1 alpha IL1 IL1-ALPHA IL1 Alpha Interleukin-1 alpha IL-1A IL1F1 Pro-interleukin-1-alpha Preinterleukin 1 alpha Interleukin 1 alpha |
Application
Immunohistochemistry staining of IL-1 alpha in spleen tissue using IL-1 alpha monoclonal Antibody.| Application Notes | IL-1 alpha antibody can be used in ELISA, and immunohistochemistry starting at 20 μg/mL.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store IL-1 alpha antibody at 4 ˚C or -20 ˚C. As with all antibodies avoid freeze/thaw cycles. |
| Storage Buffer | PBS, pH 7.4, 0.03% sodium azide. |
