| Product Name | IL-37 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Interleukin-1 Family Member 7; IL-1F7; FIL1 zeta; IL-1X; Interleukin-1 Homolog 4; IL-1H4; Interleukin-1 zeta; IL-1 zeta; IL-1RP1; IL1F7; FIL1Z, IL1H4, IL1RP1 |
| Product description | IL-37 (Interleukin-37) belongs to the IL-1 family. It binds to interleukin-18 receptor (IL-18R) but not to IL-1 receptor. It was shown to play an important role as a link between innate and adaptive immunity and it is suggested as a new player in the inflammatory and immune responses mediated by the IL-18/IL-18R axis. It was also shown to inhibit tumor growth. |
| Immunogen | Recombinant human IL-37. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | ELISAIHCIPWB |
| ELISA: (direct and indirect: 1:2,000-1:5,000), Immunohistochemistry: (1:50)Immunoprecipitation: (1:500- 1:2,000). Western Blot: (1:2,000-1:5,000 using ECL suggested blocking and dilution buffer is PBST containing 0.05% Tween 20 and 5% skim milk suggested incubation time is 1 hour at room temperature). Optimal conditions must be determined individually for each application.: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Symbol | IL37 |
|---|---|
| Alternative Names | Interleukin-1 Family Member 7 IL-1F7 FIL1 zeta IL-1X Interleukin-1 Homolog 4 IL-1H4 Interleukin-1 zeta IL-1 zeta IL-1RP1 IL1F7 FIL1Z IL1H4 IL1RP1 |
| Tissue Specificity | Recognizes human IL-37. Detects a band of ~30kDa by Western blot. |
| Application Notes | ELISA: (direct and indirect: 1:2,000-1:5,000), Immunohistochemistry: (1:50)Immunoprecipitation: (1:500- 1:2,000). Western Blot: (1:2,000-1:5,000 using ECL suggested blocking and dilution buffer is PBST containing 0.05% Tween 20 and 5% skim milk suggested incubation time is 1 hour at room temperature). Optimal conditions must be determined individually for each application.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Stable for at least 6 months after receipt when stored at -20˚C. |
| Storage Buffer | Liquid. 0.2um-filtered solution in PBS, pH 7.4. Contains no preservatives. |
