Nuclear factor of activated T-cells (NFAT) is a
transcription factor required for T-cell expression of the
interleukin 2 gene. NFAT binds to a sequence in the interleukin 2
gene enhancer known as the antigen receptor response element 2. In
addition, NFAT can bind RNA and is an essential component for
encapsidation and protein priming of hepatitis B viral polymerase.
NFAT is a heterodimer of 45 kDa and 90 kDa proteins, the smaller of
which is the product of this gene. The encoded protein binds
strongly to the 90 kDa protein and stimulates its ability to
enhance gene expression.1) Karmakar, S., et al. EMBO J. 29(19):3260-3271(2010)
Immunogen
This ILF2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 84-112 amino acids from the N-terminal region of human ILF2.
Western blot analysis in MCF-7 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.