IMPDH1 acts as a homotetramer to regulate cell growth. It is an enzyme that catalyzes the synthesis of xanthine monophosphate (XMP) from inosine-5'-monophosphate (IMP). This is the rate-limiting step in the de novo synthesis of guanine nucleotides. Defects in this gene are a cause of retinitis pigmentosa type 10 (RP10).1) Wang, J., (2008) Clin. Pharmacol. Ther. 83 (5), 711-717.
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human IMPDH1.
Key Feature
Clonality
Polyclonal
Host Species
Rabbit
Tested Applications
ELISAWB
IMPDH1 antibody can be used for detection of IMPDH1 by ELISA at 1:312500. IMPDH1 antibody can be used for detection of IMPDH1 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.:
IMPDH1 antibody can be used for detection of IMPDH1 by ELISA at 1:312500. IMPDH1 antibody can be used for detection of IMPDH1 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.:
Additional Information
Form
Liquid
Storage Instructions
For short periods of storage (days) store at 4˚C. For longer periods of storage, store IMPDH1 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Storage Buffer
Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL.