Application
Immunohistochemical analysis of paraffin-embedded human colon carcinoma tissue using Inos (Phospho-Tyr151) antibody (left) or the same antibody preincubated with blocking peptide (right).| Product Name | iNOS (phospho Tyr151) Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | HEP-NOS, NOS2, inducible |
| Product description | Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In macrophages, NO mediates tumoricidal and bactericidal actions. Also has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such COX2.1) Geller D.A., Proc. Natl. Acad. Sci. U.S.A. 90:3491-3495(1993). |
| Immunogen | iNOS (phospho Tyr151) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 151 (Q-Y-Y (p)-G-S) derived from Human iNOS . |
| Modification | p-Tyr151 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHC |
| IHC:1:50~1:200 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | HumanMouse |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | NOS2 |
|---|---|
| Alternative Names | HEP-NOS NOS2 inducible |
| Molecular Weight(MW) | 131 kDa |
| Tissue Specificity | The antibody detects endogenous levels of Inos only when phosphorylated at tyrosine 151. |
| Entrez Gene | 4843 |
|---|---|
| Protein Accession | NP_000616.3 |
Application
Immunohistochemical analysis of paraffin-embedded human colon carcinoma tissue using Inos (Phospho-Tyr151) antibody (left) or the same antibody preincubated with blocking peptide (right).| Application Notes | IHC:1:50~1:200 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store antibody at -20˚C for up to one year. |
| Storage Buffer | Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
