Application
Immunohistochemical analysis of paraffin-embedded human brain tissue using IRAK1 (Phospho-Ser376) antibody (left) or the same antibody preincubated with blocking peptide (right).| Product Name | IRAK1 (phospho Ser376) Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | IRAK1 encodes the interleukin-1 receptor-associated kinase 1, one of two putative serine/threonine kinases that become associated with the interleukin-1 receptor (IL1R) upon stimulation. IRAK1 is partially responsible for IL1-induced upregulation of the transcription factor NF-kappa B.1) Cao Z., Science 271:1128-1131(1996). |
| Immunogen | IRAK1 (phospho Ser376) antibody was raised against a peptide sequence around phosphorylation site of Serine 376 (Q-S-S (p)-M-V) derived from Human IRAK1. |
| Modification | p-Ser376 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHC |
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | IRAK1 |
|---|---|
| Alternative Names | IL1RAK IRAK mPLK |
| Molecular Weight(MW) | 76 kDa |
| Tissue Specificity | The antibody detects endogenous levels of IRAK1 only when phosphorylated at serine 376. |
| Entrez Gene | 3654 |
|---|---|
| Protein Accession | NP_001560.2 |
Application
Immunohistochemical analysis of paraffin-embedded human brain tissue using IRAK1 (Phospho-Ser376) antibody (left) or the same antibody preincubated with blocking peptide (right).| Form | Liquid |
|---|---|
| Storage Instructions | Store antibody at -20˚C for up to one year. |
| Storage Buffer | Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
