Application
Immunohistochemistry staining of IRF3 in liver tissue using IRF3 Antibody.| Product Name | IRF3 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Interferon regulatory factor 3 (IRF3) is a trascription factor activated in response to various environmental stresses including viral infection and DNA-damaging agents. IRF3 can inhibit cell growth and plays a critical role in controling the expression of genes in the innate immune response. In unstimulated cells, IRF3 is present in the cytoplasm. Viral infection results in phosphorylation of IRF3, leading to its translocation to the nucleus, where it activates promoters Suitable for use in Western Blot and Immunohistochemistry (FFPE). Other applications not tested. Detects endogenous levels of human IRF3 at 57kD. Species Crossreactivity: monkey. |
| Immunogen | IRF3 antibody was raised against a synthetic peptide (KLH - coupled) corresponding to a region around residue 300 of IRF3 (Human). |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHCWB |
| IRF3 antibody can be used in ELISA, Western Blot starting at 1:500 - 1:1000, and immunohistochemistry starting at 5 μg/mL. | |
| Species Reactivity | HumanMonkey |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | IRF3 |
|---|---|
| Alternative Names | IRF3 Interferon regulatory factor 3 IRF-3 |
Application
Immunohistochemistry staining of IRF3 in liver tissue using IRF3 Antibody.| Application Notes | IRF3 antibody can be used in ELISA, Western Blot starting at 1:500 - 1:1000, and immunohistochemistry starting at 5 μg/mL. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | IRF3 antibody should be stored long term (months) at -20 ˚C and short term (weeks) at 4 ˚C. As with all antibodies avoid freeze/thaw cycles. |
| Storage Buffer | 10 mM sodium HEPES, pH 7.5, 150 mM sodium chloride, 0.1 mg/mL BSA, 50% glycerol. |
