Histone acetyltransferase KAT2A, General control of amino acid synthesis protein 5-like 2, Histone acetyltransferase GCN5, HsGCN5, Lysine acetyltransferase 2A, STAF97, KAT2A, GCN5, GCN5L2, HGCN5
Product description
KAT2A, or GCN5, is a histone acetyltransferase (HAT) that
functions primarily as a transcriptional activator. It also
functions as a repressor of NF-kappa-B (see MIM 164011) by
promoting ubiquitination of the NF-kappa-B subunit RELA (MIM
164014) in a HAT-independent manner (Mao et al., 2009 [PubMed
19339690]).1) Terreni, M., et al. Retrovirology 7, 18 (2010) :
Immunogen
This KAT2A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 611-638 amino acids from the C-terminal region of human KAT2A.
Western blot analysis in uterus tumor cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.