Application
Antibody used in WB on HepG2 at 2.5 ug/ml (Lane A: Primary Antibody and Lane B: Primary Antibody + Blocking Peptide ).Application
Antibody used in WB on Human HepG2 at 1.25 ug/ml.Application
Antibody used in IHC on Rat brain section at: 1:500.Application
Antibody used in IHC on Rhesus macaque spinal cord at 1:300.| Product Name | KCNN2 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Action potentials in vertebrate neurons are followed by an afterhyperpolarization (AHP) that may persist for several seconds and may have profound consequences for the firing pattern of the neuron. Each component of the AHP is kinetically distinct and is mediated by different calcium-activated potassium channels. The protein encoded by KCNN2 is activated before membrane hyperpolarization and is thought to regulate neuronal excitability by contributing to the slow component of synaptic AHP. The encoded protein is an integral membrane protein that forms a voltage-independent calcium-activated channel with three other calmodulin-binding subunits. KCNN2 is a member of the KCNN family of potassium channel genes.1) Feranchak, A.P., et al., (2004) Gastroenterology 127 (3), 903-913. |
| Immunogen | Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human KCNN2. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | ELISAWB |
| KCNN2 antibody can be used for detection of KCNN2 by ELISA at 1:62500. KCNN2 antibody can be used for detection of KCNN2 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000. | |
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | KCNN2 |
|---|---|
| Alternative Names | KCNN2 SK2 hSK2 SKCA2 KCa2.2 SKCa 2 |
| Molecular Weight(MW) | 64 kDa |
Application
Antibody used in WB on HepG2 at 2.5 ug/ml (Lane A: Primary Antibody and Lane B: Primary Antibody + Blocking Peptide ).
Application
Antibody used in WB on Human HepG2 at 1.25 ug/ml.
Application
Antibody used in IHC on Rat brain section at: 1:500.
Application
Antibody used in IHC on Rhesus macaque spinal cord at 1:300.| Positive Control | 1) Cat. No. 1211 - HepG2 Cell Lysate |
|---|---|
| Application Notes | KCNN2 antibody can be used for detection of KCNN2 by ELISA at 1:62500. KCNN2 antibody can be used for detection of KCNN2 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000. |
| Form | Liquid |
|---|---|
| Storage Instructions | For short periods of storage (days) store at 4˚C. For longer periods of storage, store KCNN2 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles. |
| Storage Buffer | IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt |
