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KCNN2 antibody - middle region

Catalog Number:OM107318
OM107318
Discount Price
OM107318-100ul
1~2 Week
100ul
OM107318-50ul
50ul
OM107318-20ul
20ul
1~2 Week
Product Profile
Product Name KCNN2 antibody - middle region
Antibody Type Primary Antibodies
Immunogen The immunogen for anti-KCNN2 antibody: synthetic peptide directed towards the middle region of human KCNN2
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WB
Species Reactivity Bovine,Dog,Horse,Human,Mouse,Pig,Rabbit,Rat
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Symbol KCNN2
Gene Synonyms KCa2.2
SK2
SKCA2
hSK2
Gene Full Name Potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2
Gene Summary KCNN2 is an integral membrane protein that forms a voltage-independent calcium-activated channel with three other calmodulin-binding subunits. This protein is a member of the KCNN family of potassium channel genes. Two transcript variants encoding different isoforms have been found for KCNN2.Action potentials in vertebrate neurons are followed by an afterhyperpolarization (AHP) that may persist for several seconds and may have profound consequences for the firing pattern of the neuron. Each component of the AHP is kinetically distinct and is mediated by different calcium-activated potassium channels. KCNN2 is activated before membrane hyperpolarization and is thought to regulate neuronal excitability by contributing to the slow component of synaptic AHP.Action potentials in vertebrate neurons are followed by an afterhyperpolarization (AHP) that may persist for several seconds and may have profound consequences for the firing pattern of the neuron. Each component of the AHP is kinetically distinct and is mediated by different calcium-activated potassium channels. The protein encoded by this gene is activated before membrane hyperpolarization and is thought to regulate neuronal excitability by contributing to the slow component of synaptic AHP. The encoded protein is an integral membrane protein that forms a voltage-independent calcium-activated channel with three other calmodulin-binding subunits. This gene is a member of the KCNN family of potassium channel genes. Two transcript variants encoding different isoforms have been found for this gene.
Alternative Names KCa2.2
SK2
SKCA2
hSK2
Molecular Weight(MW) 26kDa
Sequence 231 amino acids
Database Links
Entrez Gene 3781
SwissProt ID Q6PJI0
Protein Accession NP_740721
Application

Western blot

Host: Rabbit
Target Name: KCNN2
Sample Tissue: Human Fetal Muscle
Antibody Dilution: 1.0ug/ml

Western blot

Host: Rabbit
Target Name: KCNN2
Sample Tissue: Human Fetal Lung
Antibody Dilution: 1.0ug/ml

Western blot

Host: Rabbit
Target Name: KCNN2
Sample Tissue: Human Fetal Heart
Antibody Dilution: 1.0ug/ml

Western blot

0.2-1 ug/ml
ELISA Titer: 1:62500
Positive Control: Human Muscle
Additional Information
Form Liquid
Storage Instructions Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles
Storage Buffer phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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