Application
Western blot analysis in HepG2 cell line lysates (35ug/lane).| Product Name | KCTD13 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1, hBACURD1, BTB/POZ domain-containing protein KCTD13, Polymerase delta-interacting protein 1, TNFAIP1-like protein, KCTD13, BACURD1, PDIP1, POLDIP1 |
| Product description | Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex involved in regulation of cytoskeleton structure. The BCR(BACURD1) E3 ubiquitin ligase complex mediates the ubiquitination of RHOA, leading to its degradation by the proteasome, thereby regulating the actin cytoskeleton and cell migration.1) Chen, Y., et al. Mol. Cell 35(6):841-855(2009) |
| Immunogen | This KCTD13 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 229-258 amino acids from the C-terminal region of human KCTD13. |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| For WB starting dilution is: 1:1000: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | KCTD13 |
|---|---|
| Alternative Names | BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1 hBACURD1 BTB/POZ domain-containing protein KCTD13 Polymerase delta-interacting protein 1 TNFAIP1-like protein KCTD13 BACURD1 PDIP1 POLDIP1 |
| Molecular Weight(MW) | 36 kDa |
| Sequence Similarities | Predicted species reactivity based on immunogen sequence: Bovine |
Application
Western blot analysis in HepG2 cell line lysates (35ug/lane).| Application Notes | For WB starting dilution is: 1:1000: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | Supplied in PBS with 0.09% (W/V) sodium azide. |
