NEPH1 is a member of the nephrin-like protein family,
which includes NEPH2 (MIM 607761) and NEPH3 (MIM 607762). The
cytoplasmic domains of these proteins interact with the C terminus
of podocin (NPHS2; MIM 604766), and the genes are expressed in
kidney podocytes, cells involved in ensuring size- and
charge-selective ultrafiltration (Sellin et al., 2003 [PubMed
12424224]).1) Machuca, E., et al. J. Am. Soc. Nephrol. 21(7):1209-1217(2010)
Immunogen
This KIRREL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 505-534 amino acids from the C-terminal region of human KIRREL.
Western blot analysis in MDA-MB231 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.