The galectins are a family of beta-galactoside-binding
proteins implicated in modulating cell-cell and cell-matrix
interactions. LGALS3BP has been found elevated in the serum of
patients with cancer and in those infected by the human
immunodeficiency virus (HIV). It appears to be implicated in immune
response associated with natural killer (NK) and
lymphokine-activated killer (LAK) cell cytotoxicity. Using
fluorescence in situ hybridization the full length 90K cDNA has
been localized to chromosome 17q25. The native protein binds
specifically to a human macrophage-associated lectin known as Mac-2
and also binds galectin 1.1) Davila, S., et al. Genes Immun. 11(3):232-238(2010)
Immunogen
This LGALS3BP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 383-412 amino acids from the Central region of human LGALS3BP.
Western blot analysis in mouse lung tissue lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.