The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. LGALS3BP has been found elevated in the serum of patients with cancer and in those infected by the human immunodeficiency virus (HIV). It appears to be implicated in immune response associated with natural killer (NK) and lymphokine-activated killer (LAK) cell cytotoxicity. Using fluorescence in situ hybridization the full length 90K cDNA has been localized to chromosome 17q25. The native protein binds specifically to a human macrophage-associated lectin known as Mac-2 and also binds galectin 1. [provided by RefSeq, Jul 2008]
Alternative Names
90K M2BP gp90 CyCAP BTBD17B MAC-2-BP TANGO10B
Molecular Weight(MW)
65 kDa(Observed band size: 100 kDa)
Cellular Localization
Extracellular matrix,Secreted.
Application
WB
Western blot analysis of extracts from HeLa, HepG2, K562, PC-12 cells using LGALS3BP Rabbit mAb at 1:1000.
WB
Western blot analysis of extracts from 3T3, C6 cells and Rat spleen tissue using LGALS3BP Rabbit mAb at 1:1000.
Application Notes
WB:1:1000
Additional Information
Form
Liquid
Storage Instructions
Store at -20°C.Stable for 12 months from date of receipt.
Storage Buffer
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.