This gene encodes a mitochondrial matrix protein in the
Lon family of ATP-dependent proteases. A similar E. coli protein
regulates gene expression by targeting specific regulatory proteins
for degradation. This protein binds a specific sequence in the
light and heavy chain promoters of the mitochondrial genome which
are involved in regulation of DNA replication and transcription.1) Hansen, J., et al. Neuroscience 153(2):474-482(2008)
Immunogen
This LONP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 389-418 amino acids from the Central region of human LONP1.
Western blot analysis in Hela cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.