Application
Immunohistochemistry staining of LSP1 in thymus tissue using LSP1 Antibody.| Product Name | LSP1 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | LSP1, 47 kDa actin-binding protein, 47 kDa actin binding protein, 52 kDa phosphoprotein, Leukocyte-specific protein 1, Lymphocyte-specific protein 1, Pp52, WP34 |
| Product description | LSP1 is a 52kD leukocyte-specific protein expressed in B cells, T cells, macrophages and neutrophils. The protein binds F-actin through its carboxy-terminal actin-binding repeat and regulates cytoskeletal-related cellular movement such as polarization, chemotaxis and locomotion (2-4). LSP1 is a phospho-protein and has been identified as a major substrate of MAP kinase and PKC in lymphocytes and neutrophils. The phosphorylation is possibly related to its cytoskeletal regulation function. Suitable for use in Western Blotting. Other applications not tested. Detects endogenous levels of LSP1 protein independent of phosphorylation. |
| Immunogen | LSP1 antibody was raised against amino acids 37 - 48 of LSP1 (Human). |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | WB |
| LSP1 antibody can be used in Western Blot starting at 1.5 μg/mL, immunohistochemistry starting at 10 μg/mL, and immunoprecipitation.: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | LSP1 |
|---|---|
| Alternative Names | LSP1 47 kDa actin-binding protein 47 kDa actin binding protein 52 kDa phosphoprotein Leukocyte-specific protein 1 Lymphocyte-specific protein 1 Pp52 WP34 |
Application
Immunohistochemistry staining of LSP1 in thymus tissue using LSP1 Antibody.| Application Notes | LSP1 antibody can be used in Western Blot starting at 1.5 μg/mL, immunohistochemistry starting at 10 μg/mL, and immunoprecipitation.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | LSP1 antibody should be stored long term (months) at -20 ˚C and short term (weeks) at 4 ˚C. As with all antibodies avoid freeze/thaw cycles. |
| Storage Buffer | 10 mM sodium HEPES, pH 7.5, 150 mM sodium chloride, BSA, 50% glycerol. |
