Application
Immunohistochemistry staining of MAP2K4 in kidney tissue using MAP2K4 Antibody.| Product Name | MAP2K4 (phospho Ser80) Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | MKK4, a MAP2K type protein kinase, is a member of the stress-activated protein kinase (SAPK) pathways which convey pro-apoptotic signals. MKK4 is activated by MEKK1 or MEKK2, and to a lesser extent by GCK or ASK1. MKK4 phosphorylates and activates JNK1, JNK2 and p38. MKK4 deficiency in mouse embryos led to lethality after embryonic day 12.5 and was associated with abnormal liver development. Additional studies have linked MKK4 to tumor suppression. |
| Immunogen | MAP2K4 antibody was raised against a phosphopeptide from MAP2K4 (Human). |
| Modification | p-Ser80 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHCWB |
| MAP2K4 antibody can be used in ELISA, Western Blot, and immunohistochemistry starting at 5 μg/mL. | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | MAP2K4 |
|---|---|
| Alternative Names | MAP2K4 JNK activating kinase 1 JNK-activated kinase 1 JNK-activating kinase 1 MAPK/ERK kinase 4 MAPKK4 JNKK1 PRKMK4 SAPKK1 SEK1 MEK4 MKK4 SAPK/ERK kinase 1 SERK1 JNKK MAP kinase kinase 4 MAPKK 4 MEK 4 SAPK kinase 1 SAPKK-1 SKK1 |
| Tissue Specificity | pSer80 |
Application
Immunohistochemistry staining of MAP2K4 in kidney tissue using MAP2K4 Antibody.| Application Notes | MAP2K4 antibody can be used in ELISA, Western Blot, and immunohistochemistry starting at 5 μg/mL. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | MAP2K4 antibody should be stored long term (months) at -80 ˚C and short term (days) at -20 ˚C. As with all antibodies avoid freeze/thaw cycles. |
| Storage Buffer | PBS, 0.02% sodium azide, 50% glycerol. |
