Application
Immunohistochemistry staining of MAP4K4 in skeletal muscle tissue using MAP4K4 Antibody.| Product Name | MAP4K4 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | MAP4K4 is a MSN protein kinase. The protein has a structure similar to other GCK (Group I) kinases and contains two consensus SH3 binding motifs, which have been shown to interact with the SH3 domains of the SH2/SH3 adapter protein Nck. NIK can be activated by tumor necrosis factor (TNF)-alpha. Activated NIK has been shown to activate c-Jun N-terminal kinase (JNK) and to bind and activate the plasma membrane Na-H exchanger NHE1. In NIK(-/-) mice, mesodermal and endodermal cells of the primitive streak fail to migrate to their correct location, and embryos die between embryonic day (E) 9.5 and E10.5. At least three protein isoforms have been reported. |
| Immunogen | Peptide corresponding to amino acids 931 to 947 of human NIK. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | IHCWB |
| MAP4K4 antibody can be used in ELISA, Western Blot, immunohistochemistry starting at 5 μg/mL, and immunofluorescence starting at 10 μg/mL. | |
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Unpurified |
| Gene Symbol | MAP4K4 |
|---|---|
| Alternative Names | MAP4K4 HGK HPK/GCK-like kinase HGK KIAA0687 Misshapen NIK Nck-interacting kinase HPK/GCK-like kinase Ste20 group protein kinase HGK MEKKK 4 MEKKK4 Zc1 FLH21957 MEK kinase kinase 4 |
Application
Immunohistochemistry staining of MAP4K4 in skeletal muscle tissue using MAP4K4 Antibody.| Application Notes | MAP4K4 antibody can be used in ELISA, Western Blot, immunohistochemistry starting at 5 μg/mL, and immunofluorescence starting at 10 μg/mL. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store MAP4K4 antibody at 4 ˚C or -20 ˚C. As with all antibodies avoid freeze/thaw cycles. |
| Storage Buffer | PBS, 0.02% sodium azide. |
