Application
Western blot analysis in NCI-H292 cell line lysates (35ug/lane).| Product Name | MCCC2 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | This gene encodes the small subunit of 3-methylcrotonyl-CoA carboxylase. This enzyme functions as a heterodimer and catalyzes the carboxylation of 3-methylcrotonyl-CoA to form 3-methylglutaconyl-CoA. Mutations in this gene are associated with 3-Methylcrotonylglycinuria, an autosomal recessive disorder of leucine catabolism.1) Yoshida, T., et al. Int. J. Mol. Med. 25(4):649-656(2010) Oguri, M., et al. Am. J. Hypertens. 23(1):70-77(2010) Cho, Y.S., et al. Proteins 70(1):268-272(2008) Uematsu, M., et al. J. Hum. Genet. 52(12):1040-1043(2007) Stadler, S.C., et al. Biochem. Biophys. Res. Commun. 334(3):939-946(2005) |
| Immunogen | This MCCC2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 468-496 amino acids from the C-terminal region of human MCCC2. |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| For WB starting dilution is: 1:1000 | |
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | MCCC2 |
|---|---|
| Alternative Names | Methylcrotonoyl-CoA carboxylase beta chain mitochondrial MCCase subunit beta 3-methylcrotonyl-CoA carboxylase 2 3-methylcrotonyl-CoA carboxylase non-biotin-containing subunit 3-methylcrotonyl-CoA:carbon dioxide ligase subunit beta MCCC2 MCCB |
| Molecular Weight(MW) | 61 kDa |
Application
Western blot analysis in NCI-H292 cell line lysates (35ug/lane).| Application Notes | For WB starting dilution is: 1:1000 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | Supplied in PBS with 0.09% (W/V) sodium azide. |
