Application
Immunohistochemistry staining of MCM2 in skin tissue using MCM2 Antibody.| Product Name | MCM2 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | MCM2, also called DNA replication licensing factor MCM2, Minichromosome maintenance protein 2 homolog or Nuclear Protein BM28) is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre-RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein forms a complex with MCM4, 6, and 7, and has been shown to regulate the helicase activity of the complex. This protein is phosphorylated, and thus regulated by protein kinases CDC2 and CDC7. Double serines at positions 26 and 27 are conserved in rat and mouse. High homology >88% to similar proteins from several other species. Expected broad reactivity to various lysates. |
| Immunogen | MCM2 antibody was raised against amino acids 21 - 31 of MCM2 (Human). |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | ELISAIFIHCWB |
| MCM2 antibody can be used in Western Blot, and immunohistochemistry starting at 10 μg/mL. | |
| Species Reactivity | HumanMouseRatYeast |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | MCM2 |
|---|---|
| Alternative Names | MCM2 BM28 Cell devision cycle-like 1 D3S3194 Cdc19 Cyclin-like 1 KIAA0030 Nuclear protein BM28 CDCL1 MITOTIN |
Application
Immunohistochemistry staining of MCM2 in skin tissue using MCM2 Antibody.| Application Notes | MCM2 antibody can be used in Western Blot, and immunohistochemistry starting at 10 μg/mL. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store MCM2 antibody at -20 ˚C. As with all antibodies avoid freeze/thaw cycles. |
| Storage Buffer | 0.02 M potassium phosphate, 0.15 M sodium chloride, pH 7.2, 0.01% sodium azide. |
