Application
Immunohistochemical analysis of paraffin-embedded human brain tissue using MDC1 (Phospho-Ser513) antibody (left) or the same antibody preincubated with blocking peptide (right).| Product Name | MDC1 (phospho Ser513) Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | The MDC1 protein contains a forkhead homology-associated (FHA) domain and 2 BRCA1 (MIM 113705) C-terminal motifs (BRCTs) and is required for the intra-S-phase DNA damage checkpoint.1) Nagase T., DNA Res. 3:17-24(1996). |
| Immunogen | MDC1 (phospho Ser513) antibody was raised against a peptide sequence around phosphorylation site of Serine 513 (E-R-S (p)-Q-A) derived from Human MDC1. |
| Modification | p-Ser513 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHC |
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | MDC1 |
|---|---|
| Alternative Names | IER3 NFBD1 KIAA0170 DKFZp781A0122 |
| Molecular Weight(MW) | 226 kDa |
| Tissue Specificity | The antibody detects endogenous levels of MDC1 only when phosphorylated at serine 513. |
| Entrez Gene | 9656 |
|---|---|
| Protein Accession | NP_055456.2 |
Application
Immunohistochemical analysis of paraffin-embedded human brain tissue using MDC1 (Phospho-Ser513) antibody (left) or the same antibody preincubated with blocking peptide (right).| Form | Liquid |
|---|---|
| Storage Instructions | Store antibody at -20˚C for up to one year. |
| Storage Buffer | Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
