Centromere protein U, CENP-U, Centromere protein of 50 kDa, CENP-50, Interphase centromere complex protein 24, KSHV latent nuclear antigen-interacting protein 1, MLF1-interacting protein, Polo-box-interacting protein 1, CENPU, ICEN24, KLIP1, MLF1IP, PBIP1
Product description
The centromere is a specialized chromatin domain, present
throughout the cell cycle, that acts as a platform on which the
transient assembly of the kinetochore occurs during mitosis. All
active centromeres are characterized by the presence of long arrays
of nucleosomes in which CENPA (MIM 117139) replaces histone H3 (see
MIM 601128). MLF1IP, or CENPU, is an additional factor required for
centromere assembly (Foltz et al., 2006 [PubMed
16622419]).1) Suzuki, H., et al. Anticancer Res. 27 (3B), 1423-1430 (2007) :
Immunogen
This MLF1IP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 292-319 amino acids from the C-terminal region of human MLF1IP.
Centromere protein U CENP-U Centromere protein of 50 kDa CENP-50 Interphase centromere complex protein 24 KSHV latent nuclear antigen-interacting protein 1 MLF1-interacting protein Polo-box-interacting protein 1 CENPU ICEN24 KLIP1 MLF1IP PBIP1
Western blot analysis in WiDr cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.