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MMP1 Antibody

Catalog Number:OM284882
OM284882
Discount Price
OM284882-100ul
1~2 Week
100ul
OM284882-50ul
50ul
OM284882-20ul
20ul
1~2 Week
Product Profile
Product Name MMP1 Antibody
Antibody Type Primary Antibodies
Antigen Alias MMP1, CLG, CLGN
Product description Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. MMP1 is a secreted enzyme which breaks down the interstitial collagens, types I, II, and III.Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes a secreted enzyme which breaks down the interstitial collagens, types I, II, and III. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3.1) Montero, I., (2006) J. Am. Coll. Cardiol. 47 (7), 1369-1378.
Immunogen Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human MMP1.
Key Feature
Clonality Polyclonal
Host Species Rabbit
Tested Applications ELISAIHCWB
MMP1 antibody can be used for detection of MMP1 by ELISA at 1:312500. MMP1 antibody can be used for detection of MMP1 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.:
Species Reactivity Human
Concentration 1mg/ml
Purification Protein A
Target Information
Gene Symbol MMP1
Alternative Names MMP1
CLG
CLGN
Molecular Weight(MW) 52 kDa
Database Links
Entrez Gene 4312
Protein Accession NP_002412
Application

Application

Antibody used in IHC on Human.

Application

Antibody used in WB on HT29 at 1:500 ( Lane 1: 15ug HT29 cell lysate Lane 2: 15ug HT29 cell lysate ).

Application

Antibody used in IHC on Human Intestine at 2-10 ug/ml.

Application

Antibody used in WB on Human Jurkat 1.25 ug/ml.

Application

Antibody used in WB on Equine cartilage explants at 1:800.

Application

Antibody used in IHC on Human Intestine at 4.0-8.0 ug/ml.

Application

Antibody used in IHC on Human Macrophages at 1:200.
Positive Control 1) Cat. No. 1205 - Jurkat Cell Lysate
Application Notes MMP1 antibody can be used for detection of MMP1 by ELISA at 1:312500. MMP1 antibody can be used for detection of MMP1 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.:
Additional Information
Form Liquid
Storage Instructions For short periods of storage (days) store at 4˚C. For longer periods of storage, store MMP1 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Storage Buffer IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt
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