Application
Antibody used in WB on Human HT1080 at 2.5 ug/ml.Application
Antibody used in IHC on Human Macrophage at 1:200.| Product Name | MMP1 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | MMP1, CLG, CLGN |
| Product description | Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. MMP1 is a secreted enzyme which breaks down the interstitial collagens, types I, II, and III.Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes a secreted enzyme which breaks down the interstitial collagens, types I, II, and III. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3.Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes a secreted enzyme which breaks down the interstitial collagens, types I, II, and III. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3.1) Montero, I., (2006) J. Am. Coll. Cardiol. 47 (7), 1369-1378. |
| Immunogen | Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human MMP1. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | ELISAWB |
| MMP1 antibody can be used for detection of MMP1 by ELISA at 1:312500. MMP1 antibody can be used for detection of MMP1 by western blot at 2.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | MMP1 |
|---|---|
| Alternative Names | MMP1 CLG CLGN |
| Molecular Weight(MW) | 52 kDa |
Application
Antibody used in WB on Human HT1080 at 2.5 ug/ml.
Application
Antibody used in IHC on Human Macrophage at 1:200.| Positive Control | 1) HT1080 Cell Lysate |
|---|---|
| Application Notes | MMP1 antibody can be used for detection of MMP1 by ELISA at 1:312500. MMP1 antibody can be used for detection of MMP1 by western blot at 2.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.: |
| Form | Liquid |
|---|---|
| Storage Instructions | For short periods of storage (days) store at 4˚C. For longer periods of storage, store MMP1 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles. |
| Storage Buffer | IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt |
