Multimerin is a massive, soluble protein found in
platelets and in the endothelium of blood vessels. It is comprised
of subunits linked by interchain disulfide bonds to form large,
variably sized homomultimers. Multimerin is a factor V/Va-binding
protein and may function as a carrier protein for platelet factor
V. It may also have functions as an extracellular matrix or
adhesive protein. Recently, patients with an unusual
autosomal-dominant bleeding disorder (factor V Quebec) were found
to have a deficiency of platelet multimerin.1) Davila, S., et al. Genes Immun. 11(3):232-238(2010)
Immunogen
This MMRN1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 179-207 amino acids from the N-terminal region of human MMRN1.
Western blot analysis of lysates from HLVEC, HUVEC cell line (from left to right), using MMRN1 Antibody at 1:1000 at each lane.
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.