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MOSC2 Antibody

Catalog Number:OM285004
OM285004
Discount Price
OM285004-100ul
1~2 Week
100ul
OM285004-50ul
50ul
OM285004-20ul
20ul
1~2 Week
Product Profile
Product Name MOSC2 Antibody
Antibody Type Primary Antibodies
Antigen Alias Mitochondrial amidoxime reducing component 2, mARC2, 1---, Molybdenum cofactor sulfurase C-terminal domain-containing protein 2, MOSC domain-containing protein 2, Moco sulfurase C-terminal domain-containing protein 2, MARC2, MOSC2
Product description Catalytic component of the benzamidoxime prodrug-converting complex, a complex required to reduce N-hydroxylated structures, such as benzamidoxime prodrug. Benzamidoxime is an amidine prodrug produced by N-hydroxylation which is used to enhance bioavailability and increase intestinal absorption. It is then reduced into benzamidine, its active amidine, by the benzamidoxime prodrug-converting complex.1) Havemeyer,A., et.al., J. Biol. Chem. 281 (46), 34796-34802 (2006)
Immunogen This MOSC2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 270-300 amino acids from the C-terminal region of human MOSC2.
Key Feature
Clonality Polyclonal
Isotype Ig
Host Species Rabbit
Tested Applications FACSIHC-PWB
For WB starting dilution is: 1:1000 For IHC-P starting dilution is: 1:50~100 For FACS starting dilution is: 1:10~50:
Species Reactivity Human
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Symbol MARCH2
Alternative Names Mitochondrial amidoxime reducing component 2
mARC2
1---
Molybdenum cofactor sulfurase C-terminal domain-containing protein 2
MOSC domain-containing protein 2
Moco sulfurase C-terminal domain-containing protein 2
MARC2
MOSC2
Molecular Weight(MW) 38 kDa
Database Links
Entrez Gene 54996
Protein Accession Q969Z3
Application

Application

Western blot analysis of MOSC2 using rabbit polyclonal MOSC2 Antibody using 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the MOSC2 gene.

Application

Flow cytometry analysis of Hela cells (bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Application

Formalin-fixed and paraffin-embedded human lung carcinoma reacted with MOSC2 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.

Application

Western blot analysis of MOSC2 Antibody in Hela cell line lysates (35ug/lane)
Application Notes For WB starting dilution is: 1:1000 For IHC-P starting dilution is: 1:50~100 For FACS starting dilution is: 1:10~50:
Additional Information
Form Liquid
Storage Instructions Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Storage Buffer Supplied in PBS with 0.09% (W/V) sodium azide.
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