Application
Immunohistochemistry staining of Myelin Basic Protein in brain, oligodendrocytes tissue using Myelin Basic Protein Monoclonal Antibody.| Product Name | Myelin Basic Protein Antibody, Monoclonal |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Suitable for use in ELISA, Western Blot, Immunohistochemistry and quantification of myelin basic protein. Other applications have not been tested. Recognizes residues 130-136 in human myelin basic protein (21.5kD and 18.5kD molecular forms). Species Crossreactivity: Primate, rabbit, sheep, goat, rat and mouse. The classic group of MBP isoforms (isoform 4-isoform 14) are with PLP the most abundant protein components of the myelin membrane in the CNS. They have a role in both its formation and stabilization. The smaller isoforms might have an important role in remyelination of denuded axons in multiple sclerosis. The non-classic group of MBP isoforms (isoform 1-isoform 3/Golli-MBPs) found in bone marrow and the immune system may preferentially have a role in the early developing brain long before myelination, maybe as components of transcriptional complexes, and may also be involved in signaling pathways in T-cells and neural cells. |
| Immunogen | Myelin Basic Protein monoclonal antibody was raised against amino acids 130 - 136 of Myelin Basic Protein (Human). |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG2b |
| Host Species | Mouse |
| Tested Applications | ELISAIHCWB |
| Myelin Basic Protein antibody can be used in immunocytochemistry starting at 10 μg/mL, immunohistochemistry starting at 10 μg/mL, and flow cytometry. | |
| Species Reactivity | GoatHumanMousePrimateRabbitRatSheep |
| Concentration | 1mg/ml |
| Purification | Protein G |
| Gene Symbol | MBP |
|---|---|
| Alternative Names | MBP Myelin A1 protein Myelin basic protein |
Application
Immunohistochemistry staining of Myelin Basic Protein in brain, oligodendrocytes tissue using Myelin Basic Protein Monoclonal Antibody.| Application Notes | Myelin Basic Protein antibody can be used in immunocytochemistry starting at 10 μg/mL, immunohistochemistry starting at 10 μg/mL, and flow cytometry. |
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| Form | Liquid |
|---|---|
| Storage Instructions | Myelin Basic Protein antibody should be stored at -20 ˚C. As with all antibodies avoid freeze/thaw cycles. |
| Storage Buffer | PBS, pH 7.4, contains no preservative. |
