| Product Name | Neurturin Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | NTNNeurturin |
| Product description | Human Neurturin (NTN) and Human GDNF comprise a family of TGF-beta related neurotrophic factor which have trophic influences on a variety of neuronal populations. Neurturin promotes the survival of certain sympathetic and sensory neurins through interaction with distinct set of GDNF-like receptors |
| Immunogen | Produced from sera of rabbits pre-immunized with highly pure (>98%) recombinant hNeurturin (human Neurturin). |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | ELISANeutWB |
| Neutralization: To yield one-half maximal inhibition [ND50] of the biological activity of hNeurturin (50.00 ng/mL), a concentration of 0.5 - 0.75 μg/mL of this antibody is required. ELISA: To detect hNeurturin by direct ELISA (using 100 μL/well antibody solution) a concentration of at least 0.5 μg/mL of this antibody is required. This antigen affinity purified antibody, in conjunction with compatible secondary reagents, allows the detection of 0.2 - 0.4 ng/well of recombinant hNeurturin. Sandwich: To detect hNeurturin by sandwich ELISA (using 100 μL/well antibody solution) a concentration of 0.5 - 2.0 μg/mL of this antibody is required. This antigen affinity purified antibody, in conjunction with our Biotinylated Anti-Human Neurturin (38-115) as a detection antibody, allows the detection of at least 0.2 - 0.4 ng/well of recombinant hNeurturin. Western Blot: To detect hNeurturin by Western Blot analysis this antibody can be used at a concentration of 0.1 - 0.2 μg/mL. Used in conjunction with compatible secondary reagents the detection limit for recombinant hNeurturin is 1.5 - 3.0 ng/lane, under either reducing or non-reducing conditions.: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | NRTN |
|---|---|
| Alternative Names | NTNNeurturin |
| Application Notes | Neutralization: To yield one-half maximal inhibition [ND50] of the biological activity of hNeurturin (50.00 ng/mL), a concentration of 0.5 - 0.75 μg/mL of this antibody is required. ELISA: To detect hNeurturin by direct ELISA (using 100 μL/well antibody solution) a concentration of at least 0.5 μg/mL of this antibody is required. This antigen affinity purified antibody, in conjunction with compatible secondary reagents, allows the detection of 0.2 - 0.4 ng/well of recombinant hNeurturin. Sandwich: To detect hNeurturin by sandwich ELISA (using 100 μL/well antibody solution) a concentration of 0.5 - 2.0 μg/mL of this antibody is required. This antigen affinity purified antibody, in conjunction with our Biotinylated Anti-Human Neurturin (38-115) as a detection antibody, allows the detection of at least 0.2 - 0.4 ng/well of recombinant hNeurturin. Western Blot: To detect hNeurturin by Western Blot analysis this antibody can be used at a concentration of 0.1 - 0.2 μg/mL. Used in conjunction with compatible secondary reagents the detection limit for recombinant hNeurturin is 1.5 - 3.0 ng/lane, under either reducing or non-reducing conditions.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Neurturin antibody is stable for at least 2 years from date of receipt at -20˚C. The reconstituted antibody is stable for at least two weeks at 2-8˚C. Frozen aliquots are stable for at least 6 months when stored at -20˚C. Avoid repeated freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
