| Product Name | NLRP12/NALP12 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | NACHT-, LRR- and PYD-containing Protein 12; NLRP12; PYRIN-containing APAF1-like Protein 7; Monarch-1; Regulated by Nitric Oxide; RNO |
| Product description | NALP12/NLRP12 mediates activation of caspase-1 via Asc and promotes activation of NF-kappa-B via IKK. It is involved in the building of an inflammasome complex. Defects in NLRP12/NALP12 are the cause of familial cold autoinflammatory syndrome type 2 (FCAS2). |
| Immunogen | Synthetic peptide corresponding to a aa sequence near the N-terminus of human NLRP12/NALP12. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | IPWB |
| Immunoprecipitation: (1:200). Western Blot: (1:1,000).: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Symbol | NLRP12 |
|---|---|
| Alternative Names | NACHT- LRR- and PYD-containing Protein 12 NLRP12 PYRIN-containing APAF1-like Protein 7 Monarch-1 Regulated by Nitric Oxide RNO |
| Tissue Specificity | Recognizes human NLRP12/NALP12. |
| Application Notes | Immunoprecipitation: (1:200). Western Blot: (1:1,000).: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Stable for at least 1 year after receipt when stored at -20˚C. |
| Storage Buffer | Liquid. In PBS containing 10% glycerol and 0.02% sodium azide. |
