Application
Antibody used in WB on Human HepG2 at 1.25 ug/ml.| Product Name | NR1I3 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | NR1I3, CAR, CAR-BETA, CAR-SV1, CAR-SV10, CAR-SV11, CAR-SV12, CAR-SV13, CAR-SV14, CAR-SV15, CAR-SV17, CAR-SV18, CAR-SV19, CAR-SV20, CAR-SV21, CAR-SV4, CAR-SV6, CAR-SV7, CAR-SV8, CAR-SV9, CAR1, MB67, MGC97144 |
| Product description | NR1I3 is a member of the nuclear receptor superfamily, and is a key regulator of xenobiotic and endobiotic metabolism. The protein binds to DNA as a monomer or a heterodimer with the retinoid X receptor and regulates the transcription of target genes involved in drug metabolism and bilirubin clearance, such as cytochrome P450 family members.1) Ferguson, S.S., (2005) Mol. Pharmacol. 68 (3), 747-757. |
| Immunogen | Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human NR1I3. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | ELISAWB |
| NR1I3 antibody can be used for detection of NR1I3 by ELISA at 1:62500. NR1I3 antibody can be used for detection of NR1I3 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | NR1I3 |
|---|---|
| Alternative Names | NR1I3 CAR CAR-BETA CAR-SV1 CAR-SV10 CAR-SV11 CAR-SV12 CAR-SV13 CAR-SV14 CAR-SV15 CAR-SV17 CAR-SV18 CAR-SV19 CAR-SV20 CAR-SV21 CAR-SV4 CAR-SV6 CAR-SV7 CAR-SV8 CAR-SV9 CAR1 MB67 MGC97144 |
| Molecular Weight(MW) | 40 kDa, 38 kDa, 32 kDa, 35 kDa, 37 kDa, 36 kDa, 33 kDa, 30 kDa, 35 kDa, 35 kDa, 38 kDa, 36 kDa, 40 kDa, 36 kDa, 40 kDa |
Application
Antibody used in WB on Human HepG2 at 1.25 ug/ml.| Positive Control | 1) Cat. No. 1211 - HepG2 Cell Lysate |
|---|---|
| Application Notes | NR1I3 antibody can be used for detection of NR1I3 by ELISA at 1:62500. NR1I3 antibody can be used for detection of NR1I3 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.: |
| Form | Liquid |
|---|---|
| Storage Instructions | For short periods of storage (days) store at 4˚C. For longer periods of storage, store NR1I3 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles. |
| Storage Buffer | Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL. |
