Application
Antibody used in IHC on Human Liver.Application
Antibody used in WB on Human Liver at 1.25 ug/ml.| Product Name | NR1I3 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | NR1I3, CAR, CAR1, MB67, MGC150433, MGC97144, MGC97209 |
| Product description | NR1I3 mediates the induction of transcription of cytochrome P450 (CYP) genes by phenobarbital (PB) and PB-type inducers. NR1I3 activation induces hepatic expression of detoxification enzymes and transporters and increases liver size. NR1I3 can also regulate both liver homeostasis and tumorigenesis in response to xenobiotic stresses.1) Ferguson, S.S., (2005) Mol. Pharmacol. 68 (3), 747-757. |
| Immunogen | Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human NR1I3. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | ELISAIHCWB |
| NR1I3 antibody can be used for detection of NR1I3 by ELISA at 1:62500. NR1I3 antibody can be used for detection of NR1I3 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | NR1I3 |
|---|---|
| Alternative Names | NR1I3 CAR CAR1 MB67 MGC150433 MGC97144 MGC97209 |
| Molecular Weight(MW) | 39 kDa, 38 kDa, 35 kDa, 33 kDa, 38 kDa, 40 kDa, 36 kDa, 40 kDa |
Application
Antibody used in IHC on Human Liver.
Application
Antibody used in WB on Human Liver at 1.25 ug/ml.| Positive Control | 1) Cat. No. XBL-10409 - Fetal Liver Tissue Lysate |
|---|---|
| Application Notes | NR1I3 antibody can be used for detection of NR1I3 by ELISA at 1:62500. NR1I3 antibody can be used for detection of NR1I3 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.: |
| Form | Liquid |
|---|---|
| Storage Instructions | For short periods of storage (days) store at 4˚C. For longer periods of storage, store NR1I3 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles. |
| Storage Buffer | IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt |
