Nuclear receptor subfamily 2 group C member 1, Orphan nuclear receptor TR2, Testicular receptor 2, NR2C1, TR2
Product description
This gene encodes a nuclear hormone receptor characterized
by a highly conserved DNA binding domain (DBD), a variable hinge
region, and a carboxy-terminal ligand binding domain (LBD) that is
typical for all members of the steroid/thyroid hormone receptor
superfamily. This protein also belongs to a large family of
ligand-inducible transcription factors that regulate gene
expression by binding to specific DNA sequences within promoters of
target genes. Multiple alternatively spliced transcript variants
have been described, but the full-length nature of some of these
variants has not been determined.1) Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Immunogen
This NR2C1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 516-545 amino acids from the C-terminal region of human NR2C1.
Western blot analysis in HepG2 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.