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NR4A2 Antibody

Catalog Number:OM286572
OM286572
Discount Price
OM286572-100ul
1~2 Week
100ul
OM286572-50ul
50ul
OM286572-20ul
20ul
1~2 Week
Product Profile
Product Name NR4A2 Antibody
Antibody Type Primary Antibodies
Antigen Alias NR4A2, HZF-3, NOT, NURR1, RNR1, TINUR
Product description NR4A2 is a member of the steroid-thyroid hormone-retinoid receptor superfamily. The protein may act as a transcription factor. Mutations in NR4A2 gene have been associated with disorders related to dopaminergic dysfunction, including Parkinson disease, schizophernia, and manic depression. Misregulation of NR4A2 gene may be associated with rheumatoid arthritis.This gene encodes a member of the steroid-thyroid hormone-retinoid receptor superfamily. The encoded protein may act as a transcription factor. Mutations in this gene have been associated with disorders related to dopaminergic dysfunction, including Parkinson disease, schizophernia, and manic depression. Misregulation of this gene may be associated with rheumatoid arthritis. Four transcript variants encoding four distinct isoforms have been identified for this gene. Additional alternate splice variants may exist, but their full length nature has not been determined.1) Holla, V.R., (2006) J. Biol. Chem. 281 (5), 2676-2682.
Immunogen Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human NR4A2.
Key Feature
Clonality Polyclonal
Host Species Rabbit
Tested Applications ELISAWB
NR4A2 antibody can be used for detection of NR4A2 by ELISA at 1:62500. NR4A2 antibody can be used for detection of NR4A2 by western blot at 0.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.:
Species Reactivity DogDrosophilaHumanMouseRatZebra Fish
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Symbol NR4A2
Alternative Names NR4A2
HZF-3
NOT
NURR1
RNR1
TINUR
Molecular Weight(MW) 66 kDa, 64 kDa, 68 kDa, 64 kDa, 65 kDa, 60 kDa, 68 kDa, 70 kDa
Database Links
Entrez Gene 4929
Protein Accession NP_006177
Application

Application

Antibody used in WB on Human Jurkat 0.2-1 ug/ml.
Positive Control 1) Cat. No. 1205 - Jurkat Cell Lysate
Application Notes NR4A2 antibody can be used for detection of NR4A2 by ELISA at 1:62500. NR4A2 antibody can be used for detection of NR4A2 by western blot at 0.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.:
Additional Information
Form Liquid
Storage Instructions For short periods of storage (days) store at 4˚C. For longer periods of storage, store NR4A2 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Storage Buffer Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL.
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