Application
Immunohistochemistry staining of NR5A2 in pancreas tissue using NR5A2 Antibody.| Product Name | NR5A2 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | NR5A2, B1F, B1F2, B1-binding factor, CPF, CYP7A promoter-binding factor, FTZ-F1beta, FTF, Liver receptor homolog 1, LRH1, LRH-1, HB1F, HB1F-2, Nuclear receptor phr-1, FTZ-F1, Liver receptor homolog-1, Nuclear receptor NR5A2, Receptor phr |
| Product description | Alpha1-fetoprotein transcription factor (Ftf), a NR5 fushi tarazu-like receptor, also is known as ‘human B1-binding factor’ (HB1F), 'CYP7A promoter-binding factor’ (CPF), and ‘liver receptor homolog 1’ (LRH1). Ftf has been shown to affect the transcription of hepatic genes including alpha fetoprotein encoding gene (AFP), viral hepatitis B enhancer II, and 7-alpha-hydroxylase encoding gene (CYP7A1). Ftf has also been shown to affect hepatic cholesterol metabolism and bile acid synthesis. Ftf has been shown to regulate aromatase activities in adipose tissue, and alterations in Ftf expression and/or activity in adipose tissue could have considerable effects on local estrogen production and breast cancer development. LRH has been shown to expressly strongly in gonadal tissues, and may play an important role in the regulation of gonadal function. Three isoforms of Ftf have been identified: wild type (495 aa), CPF variant 1 (contains a 46-aa insertion in the A/B domain), and CPF variant 2 (contains a 172-aa deletion within the D/E domain). |
| Immunogen | NR5A2 antibody was raised against amino acids 1 - 67 of NR5A2 (Human). |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHCWB |
| NR5A2 antibody can be used in immunohistochemistry starting at 1:50, and flow cytometry.: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | NR5A2 |
|---|---|
| Alternative Names | NR5A2 B1F B1F2 B1-binding factor CPF CYP7A promoter-binding factor FTZ-F1beta FTF Liver receptor homolog 1 LRH1 LRH-1 HB1F HB1F-2 Nuclear receptor phr-1 FTZ-F1 Liver receptor homolog-1 Nuclear receptor NR5A2 Receptor phr |
Application
Immunohistochemistry staining of NR5A2 in pancreas tissue using NR5A2 Antibody.| Application Notes | NR5A2 antibody can be used in immunohistochemistry starting at 1:50, and flow cytometry.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store NR5A2 antibody at -20 ˚C. As with all antibodies avoid freeze/thaw cycles. |
| Storage Buffer | Phosphate-buffered solution, pH 7.2, 0.09% sodium azide, 50% glycerol. |
