Programmed cell death protein 6, Apoptosis-linked gene 2 protein, Probable calcium-binding protein ALG-2, PDCD6, ALG2
Product description
This gene encodes a calcium-binding protein belonging to
the penta-EF-hand protein family. Calcium binding is important for
homodimerization and for conformational changes required for
binding to other protein partners. This gene product participates
in T cell receptor-, Fas-, and glucocorticoid-induced programmed
cell death. In mice deficient for this gene product, however,
apoptosis was not blocked suggesting this gene product is
functionally redundant.1) Vergarajauregui, S., et al. J. Biol. Chem. 284(52):36357-36366(2009)
Immunogen
This PDCD6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 19-47 amino acids from the N-terminal region of human PDCD6.
Western blot analysis in A549 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.