| Product Name | PIDD Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | p53-induced Protein with a Death Domain; Leucine-rich Repeat and Death Domain-containing Protein; Lrdd |
| Product description | PIDD promotes apoptosis downstream of the tumor suppressor as component of the DNA damage/stress response pathway that connects p53/TP53 to apoptosis. It associates with NEMO/IKBKG and RIP1 and enhances sumoylation and ubiquitination of NEMO/IKBKG which is important for activation of the transcription factor NF-kappa-B. It associates with caspase-2 and RAIDD, and induces activation of caspase-2 which is an important regulator in the apoptotic pathways. |
| Immunogen | Mouse PIDD (Death Domain). |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG2b,k |
| Host Species | Mouse |
| Tested Applications | WB |
| Western Blot: (1:1,000).: |
|
| Species Reactivity | Mouse |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | Pidd1 |
|---|---|
| Alternative Names | p53-induced Protein with a Death Domain Leucine-rich Repeat and Death Domain-containing Protein Lrdd |
| Tissue Specificity | Recognizes mouse PIDD. |
| Application Notes | Western Blot: (1:1,000).: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Stable for at least 1 year after receipt when stored at -20˚C. |
| Storage Buffer | Liquid. In PBS containing 10% glycerol and 0.02% sodium azide. |
