Application
Western blot analysis of PIK3C3 in mouse small intestine tissue lysate with PIK3C3 antibody at 1 μg/ml.| Product Name | PIK3C3 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | PIK3C3 Antibody: VPS34, hVps34, VPS34, Phosphatidylinositol 3-kinase catalytic subunit type 3, Phosphatidylinositol 3-kinase p100 subunit, PI3-kinase type 3 |
| Product description | PI 3-kinase p100 (phosphoinositide-3-kinase p100 subunit), also known as hVps34 or PIK3C3 (phosphoinositide-3-kinase class III), is a member of the PI3/PI4-kinase family (1). It is a catalytic subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate and ubiquitously expressed with a highest expression in skeletal muscle (1,2). PIK3C3 is involved in the endosome to lysosome transport and plays important roles in intracellular membrane trafficking and autophagy (3-5).1) Stopkova P, Saito T, Papolos DF, et al. Identification of PIK3C3 promoter variant associated with bipolar disorder and schizophrenia. Biol. Psychiatry 2004; 55:981-8. |
| Immunogen | PIK3C3 antibody was raised against an 18 amino acid peptide near the amino terminus of human PIK3C3. The immunogen is located within amino acids 130 - 180 of PIK3C3. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISAWB |
| PIK3C3 antibody can be used for detection of PIK3C3 by Western blot at 1 - 2 μg/ml.: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | PIK3C3 |
|---|---|
| Alternative Names | PIK3C3 Antibody: VPS34 hVps34 VPS34 Phosphatidylinositol 3-kinase catalytic subunit type 3 Phosphatidylinositol 3-kinase p100 subunit PI3-kinase type 3 |
| Molecular Weight(MW) | Predicted: 91, 98 kDa Observed: 98 kDa |
| Sequence Similarities | Predicted species reactivity based on immunogen sequence: Pig: (100%) |
| Tissue Specificity | PIK3C3 antibody is human, mouse and rat reactive. |
Application
Western blot analysis of PIK3C3 in mouse small intestine tissue lysate with PIK3C3 antibody at 1 μg/ml.| Positive Control | 1) Cat. No. 1408 - Mouse Small Intestine Tissue Lysate |
|---|---|
| Application Notes | PIK3C3 antibody can be used for detection of PIK3C3 by Western blot at 1 - 2 μg/ml.: |
| Form | Liquid |
|---|---|
| Storage Instructions | PIK3C3 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. |
| Storage Buffer | PIK3C3 antibody is supplied in PBS containing 0.02% sodium azide. |
