PPM1G is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase is found to be responsible for the dephosphorylation of Pre-mRNA splicing factors, which is important for the formation of functional spliceosome. Studies of a similar gene in mice suggested a role of this phosphatase in regulating cell cycle progression.
Immunogen
This PPM1G antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 150-180 amino acids from the Central region of human PPM1G.
Protein phosphatase 1G Protein phosphatase 1C Protein phosphatase 2C isoform gamma PP2C-gamma Protein phosphatase magnesium-dependent 1 gamma PPM1G PPM1C
Western blot analysis of hPPM1G-C164 in 293 cell line lysates (35ug/lane)
Application
Western blot analysis of hPPM1G-C164 in mouse heart tissue lysates (35ug/lane)
Application Notes
For WB starting dilution is: 1:1000
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.