This gene encodes a constant regulatory subunit of protein
phosphatase 2. Protein phosphatase 2 is one of the four major
Ser/Thr phosphatases, and it is implicated in the negative control
of cell growth and division. It consists of a common heteromeric
core enzyme, which is composed of a catalytic subunit and a
constant regulatory subunit, that associates with a variety of
regulatory subunits. The constant regulatory subunit A serves as a
scaffolding molecule to coordinate the assembly of the catalytic
subunit and a variable regulatory B subunit. This gene encodes an
alpha isoform of the constant regulatory subunit A. Alternatively
spliced transcript variants have been described. [provided by
RefSeq].1) Jones, S., et al. Science 330(6001):228-231(2010)
Immunogen
This PPP2R1A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 454-481 amino acids from the C-terminal region of human PPP2R1A.
Western blot analysis in MDA-MB231 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.