This is a receptor for the anterior pituitary hormone prolactin (PRL). Isoform 4 is unable to transduce prolactin signaling. Isoform 6 is unable to transduce prolactin signaling1) Boutin J. M, et al. Mol. Endocrinol. 3:1455-1461 (1989) Kline J. B, et al. J. Biol. Chem. 274:35461-35468 (1999) Hu Z. Z, et al. J. Clin. Endocrinol. Metab. 84:1153-1156 (1999)
Immunogen
PRLR antibody was raised against a peptide sequence around aa.25~29 (Q-L-P-P-G) derived from Human PRLR.