RAMP3 is a member of the RAMP family of single-transmembrane-domain proteins, called receptor-activity-modifying proteins. RAMPs are type I transmembrane proteins with an extracellular N terminus and a cytoplasmic C terminus. RAMPs are required to transport calcitonin-receptor-like receptor (CRLR) to the plasma membrane. CRLR, a receptor with seven transmembrane domains, can function as either a calcitonin-gene-related peptide (CGRP) receptor or an adrenomedullin receptor, depending on which members of the RAMP family are expressed. Co-expression of RAMP3 with CRLR results in the production of a functional adrenomedullin receptor.
Immunogen
RAMP3 antibody was raised against a synthetic peptide corresponding to N-Terminal residues of RAMP3 (Human).
Key Feature
Clonality
Polyclonal
Host Species
Rabbit
Tested Applications
ELISAIHCWB
RAMP3 antibody can be used in ELISA starting at 1:3000 - 1:6000, Western Blot starting at 1:3000 - 1:6000, immunohistochemistry starting at 10 μg/mL, and immunoprecipitation
Immunohistochemistry staining of RAMP3 in breast (formalin-fixed paraffin embedded) tissue using RAMP3 Antibody.
Application Notes
RAMP3 antibody can be used in ELISA starting at 1:3000 - 1:6000, Western Blot starting at 1:3000 - 1:6000, immunohistochemistry starting at 10 μg/mL, and immunoprecipitation
Additional Information
Form
Liquid
Storage Instructions
Store RAMP3 antibody at 4 ˚C or -20 ˚C. As with all antibodies avoid freeze/thaw cycles.