Application
Western Blot at 1:2000 dilution + human lung lysate Lysates/proteins at 20 ug per lane.Application
Western Blot at 1:1000 dilution + mouse brain lysate Lysates/proteins at 20 ug per lane.| Product Name | RAMP3 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Receptor activity-modifying protein 3, Calcitonin-receptor-like receptor activity-modifying protein 3, CRLR activity-modifying protein 3, RAMP3 |
| Product description | The protein encoded by this gene is a member of the RAMP family of single-transmembrane-domain proteins, called receptor (calcitonin) activity modifying proteins (RAMPs). RAMPs are type I transmembrane proteins with an extracellular N terminus and a cytoplasmic C terminus. RAMPs are required to transport calcitonin-receptor-like receptor (CRLR) to the plasma membrane. CRLR, a receptor with seven transmembrane domains, can function as either a calcitonin-gene-related peptide (CGRP) receptor or an adrenomedullin receptor, depending on which members of the RAMP family are expressed. In the presence of this (RAMP3) protein, CRLR functions as an adrenomedullin receptor.1) Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010) |
| Immunogen | This RAMP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 90-118 amino acids from the C-terminal region of human RAMP3. |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| For WB starting dilution is: 1:1000: |
|
| Species Reactivity | HumanMouse |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | RAMP3 |
|---|---|
| Alternative Names | Receptor activity-modifying protein 3 Calcitonin-receptor-like receptor activity-modifying protein 3 CRLR activity-modifying protein 3 RAMP3 |
| Molecular Weight(MW) | 17 kDa |
Application
Western Blot at 1:2000 dilution + human lung lysate Lysates/proteins at 20 ug per lane.
Application
Western Blot at 1:1000 dilution + mouse brain lysate Lysates/proteins at 20 ug per lane.| Application Notes | For WB starting dilution is: 1:1000: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | Supplied in PBS with 0.09% (W/V) sodium azide. |
