Meiotic recombination protein REC8 homolog, Cohesin Rec8p, REC8, REC8L1
Product description
This gene encodes a member of the kleisin family of SMC
(structural maintenance of chromosome) protein partners. The
protein localizes to the axial elements of chromosomes during
meiosis in both oocytes and spermatocytes. In the mouse, the
homologous protein is a key component of the meiotic cohesion
complex, which regulates sister chromatid cohesion and
recombination between homologous chromosomes. Multiple
alternatively spliced variants, encoding the same protein, have
been found for this gene.1) Aston, K.I., et al. Hum. Reprod. 25(6):1383-1397(2010)
Immunogen
This REC8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 194-222 amino acids from the Central region of human REC8.
Western blot analysis in K562 cell line lysates (35ug/lane).
Application
Western Blot at 1:1000 dilution + human testis lysate Lysates/proteins at 20 ug per lane.
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.